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Ac-CoA Synthase Inhibitor1
CAS No. 508186-14-9
Ac-CoA Synthase Inhibitor1 ( Ac-CoA Synthase Inhibitor I | MDK6149 | ACSS2 Inhibitor )
产品货号. M18677 CAS No. 508186-14-9
ACSS2 抑制剂是乙酸依赖性乙酰辅酶 A 合成酶 2 (ACSS2) 的最有效和特异性的抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥332 | 有现货 |
|
| 5MG | ￥527 | 有现货 |
|
| 10MG | ￥826 | 有现货 |
|
| 25MG | ￥1515 | 有现货 |
|
| 50MG | ￥2649 | 有现货 |
|
| 100MG | ￥3953 | 有现货 |
|
| 500MG | ￥8586 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Ac-CoA Synthase Inhibitor1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述ACSS2 抑制剂是乙酸依赖性乙酰辅酶 A 合成酶 2 (ACSS2) 的最有效和特异性的抑制剂。
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产品描述MDK-6149, also known as ACSS2 Inhibitor or Ac-CoA Synthase Inhibitor I, is a Ac-CoA Synthase Inhibitor. MDK-6149 has CAS#508186-14-9. It was first reported in 2014. Cell. 159, 1591. For the convenience of scientific communication, we temporally name it as MDK-6149. The last 4 digit of its CAS# was used for name.
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体外实验Ac-CoA Synthase Inhibitor1 inhibits cellular [14C]acetate uptake into both lipids and histones with an IC50 of 5 μM. Ac-CoA Synthase Inhibitor1 inhibits the ability of HepG2 cells to incorporate [14C]acetate into lipids with IC50 of 6.8 μM. Ac-CoA Synthase Inhibitor1 inhibits HepG2 utilization of [14C]acetate for histone acetylation with IC50 of 5.5 μM.
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体内实验——
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同义词Ac-CoA Synthase Inhibitor I | MDK6149 | ACSS2 Inhibitor
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通路Immunology/Inflammation
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靶点IκB kinase (IKK)
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受体ACSS2
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研究领域——
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适应症——
化学信息
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CAS Number508186-14-9
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分子量410.51
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分子式C20H18N4O2S2
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 100 mg/mL; 243.60 mM
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SMILESCOCCNC(=O)Nc2cc3nc(c1cccs1)c(nc3cc2)c4cccs4
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化学全称1-(2,3-di(Thiophen-2-yl)quinoxalin-6-yl)-3-(2-methoxyethyl)urea
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Comerford SA,etal.Acetate dependence of tumors.Cell. 2014 Dec 18;159(7):1591-602.
产品手册
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